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Registered users can submit a thread (each thread is a single question) on any autoimmune, thyroid or health-related topic – including questions about your pet! Questions will be answered by Elaine Moore.  Because this is not a community forum, members will not be able to reply to threads once questions are asked and answered. Questions may be edited for brevity and grammar. If you need technical help, contact Admin.

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 3/8/2010 12:44 PM
 
purelife
No Ranking

Joined: 2/11/2010
Posts: 19

Dear Elaine,

“The rise in TSH even after a dose increase suggests your dose may still be too high. I can't remember if you were tested for thyroid antibodies but after miscarriage people can develop postpartum thyroiditis, a condition that causes a temporary (2 months or so) period of hyperthyroidism followed by a similar period of hyperthyroidism. What tests did you have to confirm your Graves' disease?”

With reference to your reply above, my dosage was reduced from 50mg to 25mg PTU, it was not increased. Usually TSH will rise after a dose reduction? My miscarriage happened at 6 weeks, which is very early loss. Will I develop postpartum thyroiditis?

My previous antibody result is TSI 135% and TPO 93 iu/ml

From Jane.

 
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 3/8/2010 3:27 PM
 
Elaine
1st Level Poster

Joined: 8/1/2008
Posts: 1683

Hi Jane,

Sorry, that was a typo. I knew your dose had been decreased and with a decreased dose your thyroid levels should rise and you'd expect your TSH level to fall. Your TSH could have already been on the rise from before your dose was changed since you had symptoms of hypothyroidism. Or it could be rising if you're spontaneously moving into hypothyroidism. That's why I thought of postpartum thyroiditis (PPT).

PPT can occur after any pregnancy even if it's a very short duration. Your elevated TSI suggests you do have Graves' disease. However, Graves' that develops during pregnancy or during the postpartum period can run a course similar to that of PPT. For this reason, it's a good idea to watch for symptoms of hypothyroidism and ask to have your labs checked sooner if you notice any. Best, Elaine
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