Oxidativee stress is a known autoimmune disease trigger. Oxidative stress refers to the production of free radicals that linger in the circulation inciting an immune response.

Food intolerances, such as gluten sensitivity or intolerances to eggs, dairy, peanuts or soy, contribute to oxidative stress by their induction of pro-inflammatory cytokines.

In one study on chronic fatigue, Toronto researchers found that dietary modifications and dietary supplements may provide antioxidants that combat the effects of oxidative stress. Recommended supplements include glutathione, N-acetylcysteine, alpha-lipoic acid, CoQ10, melatonin, oligomeric proanthocyanidins, Ginkgo biloba and bilberry.

Identifying food intolerances and making dietary modifications are essential for reducing the oxidative stress linked to chronic inflammation.  Additional studies have shown benefits from probiotics used to counter the increased anaerobic bacterial population that may accompany oxidative stress.

AC Logan and C Wong, "Chronic fatigue syndrome: oxidative stress and dietary modifications," Alternative Medicine Review, 2001, Oct; 6(5): 450-9.