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THE Q & A

Welcome to The Q&A with Elaine Moore. Registered members are invited to ask any question of Elaine Moore on autoimmune diseases, Graves' disease, other thyroid diseases and subconditions, laboratory work, traditional and complementary medicine, triggers and environmental influences, thyroid and immune disorders in pets and animals, and other relevant areas of inquiry.

Each thread represents one question with one answer and will only appear at the time it is answered. Once answered, further replies cannot be made to the same thread since each thread represents only one question. A new thread will need to be started for additional questions.

Questions are answered solely by Elaine Moore, a medical writer and clinical laboratory scientist, MT, CLS, with more than 30 years of experience in immunology. Moore has also authored and edited over a dozen books in the area of health sciences and is an editor for McFarland Publisher's Health Topics Series.


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 3/3/2012 4:46 AM
 
Hi Elaine,

You may recall my last question about thyroid antibodies, thank you so much for the clarification that you provided!

I recently came across some information that surprised me, since my Endo or Gynecologist never mentioned anything to me. I heard that in Graves' patients that are pregnant, that it's possible for the antibodies to pass through the placenta to the fetus. This is very alarming to me since I'm trying to conceive, or at least want to in the near future (I would never wish Graves' on anyone especially not my own child). Can you please clarify this for me?

Any insight that you can provide is more than appreciated!

Thanks in advance!

Best,
SF
New Post
 3/4/2012 3:38 PM
 

Hi SF,

Yes, thyroid antibodies can cross the placental barrier as can most IgG immunoglobulins. The real problems are seen in women who have had RAI because RAI dramatically increases TSI levels and is more likely to cause hyperthyroidism.

In women on ATDs TSI levels aren't usually very high and these levels fall during pregnancy. Most doctors will test TSI levels in the first and third trimester to make sure there isn't a sudden spike. Problems of neonatal hyperthyroidism caused by TSI are seen in less than 1% of patients. Best, Elaine

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TO USERS: Q&A posts are visible to all readers. Users can delete their own threads at any time. Users must provide information which is true and correct to the best of their knowledge as well as provide sources or references to any health / medical information if not taken from personal experience. All users including the moderator must behave at all times with respect and honesty. Advertising and self-promotion is not allowed. The moderator or site administrator has the right to ban users with or without warning for not following the basic rules of this site. All posts by default are not to be considered that of medical professionals unless otherwise indicated. As sole moderator, Moore has no conflicts of interest in the sponsorship of this forum.

 

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