Uveitis
An Inflammatory Eye Condition
The Uvea
Uveitis is an eye condition that can occur as an autoimmune disorder or as a result of injury, infection, or exposure to toxins. Uveitis is characterized by inflammation of the middle layer of the eye, which is known as the uvea. The uvea is composed of three structures:
- The iris—the colored structure of the eye surrounding the pupil
- The ciliary body—the muscle that supports the iris and focuses the lens
- The choroids-a layer containing the eye’s blood vessels located between the inner retina and the white of the eye (sclera)
Accompanying Disorders
As an autoimmune disorder, uveitis may occur alone or it may accompany other systemic autoimmune diseases such as rheumatoid arthritis, Bechet syndrome, sarcoidosis, Kawasaki disease, Reiter disease, psoriasis, ulcerative colitis, multiple sclerosis, systemic lupus erythematosus, or ankylosing spondylitis. Uveitis may also occur in AIDS, cytomegalovirus infection, syphilis, tuberculosis, Lyme disease, and in fungal infections.
Affected Eye Structures
Uveitis may cause inflammation of all three structures that make up the uvea. Alternately, only one of the structures may be affected. For instance, in the type of uveitis affecting only the iris, the condition is caller iritis, or anterior uveitis. Intermediate uveitis is also known as iridocyclitis, and posterior uveitis is known as choroiditis or chorioretinitis.
Types of Uveitis
The most common type of uveitis is anterior uveitis, which represents 75 to 90 percent of all cases, and involves inflammation in the front part of the eye. Anterior uveitis is characterized by flares lasting from a few days to a few weeks with appropriate treatment alternating with relapses.
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