ADVANCES IN GRAVES' DISEASE
GRAVES' DISEASE: A PRACTICAL GUIDE
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Hi Elaine,
Thank you for your latest reply to my rambling one. I'll try to keep this one shorter. Thank you also for your friendly approach and sharing your vast knowledge with us all.
I've bought some selenium and take 200mcg per day at the moment in the hope that it will help shrink my functioning nodules. I'm a little confused with the role of selenium though as I noticed you advised someone else that selenium is good at helping T4 into T3. I'm now concerned perhaps that it will do that for me and I don't think I need it to as my T3 level has been consistently higher than the range levels since testing me began. I also would like to ask about TPO antibody negative levels as that's what mine is apparently. I've only been tested for that once, in August but that was the result. So is selenium still ok to take if there are only nodules to shrink and no antibodies to reduce?
I hope you have a relaxing bank holiday and thank you again for all your help.
Hi Teddyette,
Good point. Selenium is needed for proper thyroid hormone production and metabolism and low levels can contribute to autoimmunity. Thus, it's needed for the optimal conversion of T4 into T3. In your case, nodules are producing too much T3. I was thinking you had TPO positive antibodies but if they're negative autoimmunity isn't the problem. Selenium, though, could help in restoring normal thyroid function.
In the U.S. nodules are often caused by hypothyroidism and excess dietary iodine. In European countries, nodules are more likely to occur because of low iodine levels. Low levels of selenium and zinc could also contribute to the problem. I wouldn't take more than 200 mcg selenium and go from there. Take care, Elaine
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