Been just over a year for my 14 year old daughter's Graves journey and things are going generally well considering where we have come from along this journey. What a ride! Grateful for this resource as the local children's hospital was pushing hard for surgery. It may be in our future but I want to give her body the chance first.

We are gradually decreasing her methimazole dose and most recent rx was 2.5 mg every am and 2.5 mg in the pm but two days on, 1 day off. Her most recent labs are below from 8/3. FT3 is throwing me off - just compensation for her leaving toward a hypo state? Our next regimen change is to continue 2.5 mg every am and 2.5 mg every other night. We have monthly labs (my saving grace!) so guessing the next step down might be two days off, one day on in the evening? Too gradual of a decrease? Any advice is appreciated.

In addition to methimazole: probiotic, glutamine, selenium (200), Vitamin D 2000 IU, Vitamin B complex, mangnesium/calcium complex, omega 3s.

A recent naturopathic practitioner suggested adding Transfer Factor Multi-Immune by Researched Nutritionals. Only doing half dose though.

Thank you for this forum and all of the incredible experience.

8-3-2017:
TSH 1.74 (0.40-6.40)
FT3 4.2 (2.1-4.1)
FT4 0.84 (0.61-1.85)

7-13-2017:
TSH 0.85 (0.40-6.40)
FT3 3.1
FT4 0..84

Hi,
It really is better to take the same dose daily and the guidelines are to use the lowest dose needed to keep FT4 near the high end of the reference range. Your daughter's TSH result also suggests that her dose is too high because most patients have no or very little TSH during treatment. I'd think that a daily dose of 2.5 mg would be adequate and it may even need to be lowered to 1.25 mg daily. A dose as low as 0.5 mg is effective, and you're correct in that too low of an FT4 can cause a compensatory rise in FT3. best, elaine